For UIST the formula used depends on the number of reads performed. For data taken with fewer than 13 reads, the formula used is:
For data taken with between 13 and 51 reads the formula used is:
For data taken with more than 51 reads the variance due to readnoise is:
For all formulas RN is the readnoise in electrons, N is the number of reads, and gain is the detector gain in electrons per ADU.
ORAC-DR -- spectroscopy data reduction